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Diagnosis and significance of pulmonary microvascular disease in diabetes

Tetrahedron 63(52):1284512852 Acknowledgements This work was supported by the National Natural Science Foundation of China (32201053) and the Beijing Institute of Technology Research Fund Program for Young Scholars (3100012222222)

1 Introduction Cancer is still regarded as one of the topmost life-threatening disorders in the world, and conventional therapeutic approaches chemotherapy, radiotherapy, immunotherapy are limited by marked toxicity, resistance and relapse rates ( in vitro and in vivo research on the ability of honey to influence tumor growth, metastatic behavior, and chemosensitization, as well as clinical studies focusing on its role in the treatment-related toxicity

doi: 10.1007/7854_2020_182 105 LoiB.MaccioniP.LobinaC.CaraiM

Indeed, metabolic alterations exerted by T2DM promote depolarization of mitochondria and disruption of regular proteolytic processing of PTEN-induced kinase 1 (PINK1), consequently triggering the initiation of mitophagy